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Figure 1. The cyclooxygenase (COX)-1 and -2 pathway. Prostaglandins (PG) are formed by specific isomerases from the COX product PGH2. They act through G protein transmembrane receptors.
Abbreviations: IP, prostacyclin receptor; TP, thromboxane receptor; DP, PGD2 receptor, EP, PGE2 receptor, FP, PGF2
receptor.
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