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Hematology 2007

The Antiphospholipid Syndrome

Jacob H. Rand

Correspondence: Jacob H. Rand, MD, Department of Pathology, Montefiore Medical Center, 111 East 210th St, Bronx, NY 10467; phone: (718) 920-6430; jrand{at}montefiore.org

Abstract

The antiphospholipid syndrome (APS) is an autoimmune thrombophilic condition that is marked by the presence of antibodies that recognize phospholipid-binding proteins. The clinical manifestations of APS include vascular thrombosis and pregnancy complications, especially recurrent spontaneous miscarriages. This article provides an update on diagnostic and therapeutic approaches to this disorder.


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Copyright © 2007 by the American Society of Hematology.