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Hematology 2007

Thrombophilia: Common Questions on Laboratory Assessment and Management

John A. Heit

Correspondence: John A. Heit, M.D., Stabile 6-Hematology Research, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905; phone 507-284-4634; fax 507-266-9302

Abstract

Thrombophilia is an inherited or acquired predisposition to thrombosis. This article reviews the clinical manifestations of thrombophilia and addresses common questions on laboratory assessment and management: what are the potential indications for thrombophilia testing, who should be tested, what tests should be requested, when should testing be performed, and how should the test results affect primary prevention, acute therapy, and secondary prophylaxis of thrombosis.


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Copyright © 2007 by the American Society of Hematology.