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Hematology 2006
© 2006 The American Society of Hematology

Perioperative Evaluation of Bleeding Diathesis

Lawrence L.K. Leung

Correspondence: Lawrence Leung, MD, VA Palo Alto HCS, Medical Service, B2-125, 3801 Miranda Ave., Palo Alto CA 94304; Phone 650-493-5000 ext 65742; Fax 650-856-8024; Email lawrence.leung{at}stanford.edu

Abstract

The differential diagnosis of a long APTT with a normal prothrombin time can be due to either a clotting factor deficiency or the presence of an inhibitor, which can be distinguished by using a plasma-mixing study. The various clotting factor deficiency states are reviewed. Clinical bleeding following cardiac bypass surgery due to acquired factor V and thrombin antibodies is also reviewed.


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Copyright © 2006 by the American Society of Hematology.