Hematology
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Hematology 2006
© 2006 The American Society of Hematology

The Management of Patients with Limited-Stage Classical Hodgkin Lymphoma

Mary K. Gospodarowicz and Ralph M. Meyer

Correspondence: Ralph M. Meyer, MD, FRCP; Queens University, 10 Stuart St., Kingston, ON K7L 3N6, Canada; Phone 613-533-6430; Fax 613-533-6511; Email rmeyer{at}ctg.queensu.ca

Abstract

The term limited-stage Hodgkin lymphoma refers to those patients with stage I–II disease and an absence of bulky disease. Among those patients with classical Hodgkin lymphoma, approximately one-third of patients will fall into this category. As long-term disease control can now be anticipated in more than 90% of these patients, management strategies must increasingly address the need to reduce the long-term treatment-related risks. Current treatment options include use of combined modality therapy that includes an abbreviated course of chemotherapy and involved-field radiation or treatment with chemotherapy, currently consisting of ABVD, as a single modality. The choice of treatment between these two options involves specific trade-offs that must balance issues of disease control against long-term risk of late effects.


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Copyright © 2006 by the American Society of Hematology.